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Ascorbic acid, a water-soluble vitamin, is essential for the synthesis of collagen and intercellular material. Deficiency develops when the dietary intake is inadequate since humans are unable to form their own ascorbic acid. Thus, ascorbic acid is normally given orally in the treatment and prevention of deficiency.
Zinc is an essential element of nutrition and traces are present in a wide range of foods. It is a constituent of many enzyme systems and is present in all tissues. Features of zinc deficiency includes growth retardation and defects of rapidly -dividing tissues such as skin, the immune system, and the intestinal mucosa.